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2017 8/Dec

Endocarditis due to Gram-negative organisms is infrequent. Gram-negative organisms are responsible for <4% of cases worldwide. Infective endocarditis caused by Gram-negative bacteria is a severe disease and presents a high rate of complications and high mortality. It often has a nosocomial origin, and it is caused by resistant organisms. HACEK organisms include: Haemophilus species Actinobacillus […]

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2017 6/Dec

Cephalosporins are β-lactam antibiotics (penicillin-family) with bactericidal effect. They disrupt cell synthesis by inhibiting enzymes in the cell wall of bacteria. There are five generations of cephalosporins. First-generation cephalosporins are most active against gram-positive bacteria, particularly Staphylococcus aureus. Second-generation cephalosporins are often used for polymicrobial infections that include gram-negative bacilli and gram-positive cocci. Third-generation cephalosporins have excellent […]

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