My Blog Posts

2018 10/Jul

Hemoglobin (Heme + Globin) is a heterotetramer composed of four polypeptide subunits (2 α and 2 β), each with a prosthetic heme group plus a globin chain. The heme group is formed of a heterocyclic ring, known as a porphyrin which contains an iron (Fe) atom in its center. Usually, the Fe is in the […]

Keep Reading
2018 20/May

Disseminated intravascular coagulation (DIC) is a syndrome resulting from the inappropriate activation of blood coagulation and formation of microvascular thrombi. During the process, consumption of platelets and coagulation factor occur. In some cases, activation of the fibrinolytic pathway may cause severe bleeding. If sufficiently severe, DIC can produce multiple organ dysfunction syndrome (MODS). Commonly patients with DIC have alterations in […]

Keep Reading
2018 21/Feb

Anemia is strictly defined as a decrease in red blood cell (RBC) mass or blood hemoglobin concentration. The prevalence of anemia in population studies of healthy, nonpregnant people depends on the hemoglobin (Hb) levels chosen for the lower limit of normal values. The World Health Organization (WHO) anemia definition is Hb levels <12.0 g/dL in women and […]

Keep Reading
2018 17/Jan

Definition: severe elevation in WBC (> 50,000 cells/mm³) caused by reactive causes outside the bone marrow. It’s a normal physiologic response to infection or stress. The diagnostic workup consists of the exclusion of chronic myelogenous leukemia (CML) and chronic neutrophilic leukemia (CNL) and the detection of an underlying cause. The diagnosis characteristics are marked mature […]

Keep Reading