Bcl-2 (B-cell lymphoma-2gene) is a member of Bcl-2 family, which contains Bcl-2, Bcl-xi, Bax, Bak, Bid, and Bad. Bcl-2, localized mainly on the outer membrane of the mitochondrion, is a very important antiapoptosis factor, by preventing the release of cytochrome C and then restraining the activation of the caspase, which is crucial for cell apoptosis. […]

Keep Reading